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Chemical Biology of Nucleic Acids: Fundamentals and Clinical Applications Erdmann, Volcker A Pdf

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 							This volume contains 29 engrossing chapters contributed by worldwide, leading research groups in the field of
chemical biology. Topics include pre-biology; the establishment of the genetic code; isomerization of RNA; damage of
nucleobases in RNA; the dynamic structure of nucleic acids and their analogs in DNA replication, extra- and
intra-cellular transport; molecular crowding by the use of ionic liquids; new technologies enabling the modification of
gene expression via editing of therapeutic genes; the use of riboswitches; the modification of mRNA cap regions; new
approaches to detect appropriately modified RNAs with EPR spectroscopy and the use of parallel and high-throughput
techniques for the analysis of the structure and new functions of nucleic acids. This volume discusses how chemistry can
add new frontiers to the field of nucleic acids in molecular medicine, biotechnology and nanotechnology and is not only
an invaluable source of information to chemists, biochemists and life scientists but will also stimulate future
research.
   						

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